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A: People who are pregnant or breastfeeding, those with severe gastrointestinal motility disorders such as gastroparesis, and anyone with a known hypersensitivity to the ingredient

If coffee consistently worsens your symptoms, it's worth discussing with your healthcare provider, who can recommend changes based on your individual needs

A separate 2025 trial in NEJM Evidence (Shah et al.) in adults with T1D and obesity on AID found that around one in three semaglutide-treated participants met a combined goal of improved time in range, low hypoglycemia, and at least 5% weight loss

Uamek-Kozio M, Czuczwar SJ, Januszewski S, Pluta R , et al